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alveolar partial pressure of oxygen will be reduced to 69.62 mmHg in account of a normal saturated vapor pressure of 47 mmHg, a normal alveolar carbon dioxide partial pressure of 40 mmHg, and a 0.8 normal respiratory gas exchange ratio. For non-pressurized aircraft pilots, the degree of alveolar hypoxia is even more severe should they operate above 6309 ft (1923 m) without oxygen supplement. Because of the lower alveolar partial pressure of oxygen, the arterial partial pressure of oxygen will consequently decline, leading to a decrease in hemoglobin oxygen saturation and

volume of the basal ganglia upon diagnosis. 4 To our knowledge, this is the first described case of a neuroacanthocytosis in a professional aviator. CASE REPORT A 56-yr-old male commercial airline pilot with over 25,000 h of flying time presented to the clinic for a fitness-for-duty evaluation after peers noted a decrease in the pilot’s concentration as well as behavioral changes in the cockpit. The pilot’s peers reported that he was devoting increasing amounts of time to noncritical tasks such as repeatedly cleaning knobs and switches. Additionally, the

function and withstand decelerations for a specified range of occupant all-up-mass (AUM) to maintain peak G-forces below injurious levels during a crash sequence. AUM not only includes the individual, but must also allow for any uniform items, personal protective equipment, or survival gear that is worn by or harnessed to the pilot. Although safety ratings typically remain fixed for the airframe following initial design and testing phases, the weight of such aircrew-borne equipment has incrementally increased over time and can be significant, exceeding 20 kg in some