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Denosumab as a Pharmacological Countermeasure Against Osteopenia in Long Duration Spaceflight
Anthony Rengel,
Vienna Tran, and
Li Shean Toh
Article Category: Research Article
Volume/Issue: Volume 94: Issue 5
Online Publication Date: May 01, 2023
DOI: 10.3357/AMHP.6053.2023
Page Range: 389 – 395

application. 8 The aim of this literature review is to understand the current literature pertaining to denosumab use and its potential in long-duration spaceflight. This paper summarizes current knowledge of pharmacological countermeasures pertaining to bone health in spaceflights, discussing the potential benefits and disadvantages of both denosumab and alendronate. It then proposes further studies to assess the stability of monoclonal antibody therapies in spaceflight and the efficacy of denosumab as a countermeasure against microgravity-induced osteopenia

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Lawrence W. Steinkraus
Article Category: Research Article
Volume/Issue: Volume 74: Issue 8
Online Publication Date: Aug 01, 2003
DOI:
Page Range: 869 – 873
Robin Low,
Timothy Teoh,
Adrian Loh, and
Allan Ooi
Article Category: Case Report
Volume/Issue: Volume 79: Issue 11
Online Publication Date: Nov 01, 2008
Page Range: 1067 – 1070
Mauricio J. Falcai,
Mario J. Q. Louzada,
Francisco J. A. de Paula,
Rodrigo Okubo, and
Jose B. Volpon
Article Category: Other
Volume/Issue: Volume 83: Issue 12
Online Publication Date: Dec 01, 2012
Page Range: 1176 – 1180
Jesper S. Thomsen,
Boris V. Morukov,
Laurence Vico,
Christian Alexandre,
Peter I. Saparin, and
Wolfgang Gowin
Article Category: Research Article
Volume/Issue: Volume 76: Issue 10
Online Publication Date: Oct 01, 2005
DOI:
Page Range: 915 – 922
Pengfei Yang,
Bin Jia,
Chong Ding,
Zhe Wang,
Airong Qian, and
Peng Shang
Article Category: Research Article
Volume/Issue: Volume 80: Issue 2
Online Publication Date: Feb 01, 2009
Page Range: 88 – 93
Fig. 1.; Article selection flowchart.
Anthony Rengel,
Vienna Tran, and
Li Shean Toh
Fig. 1.
Fig. 1.

Article selection flowchart.


Honglei Ma,
Yu Zhu,
Yanhua Xiao,
Guanghan Kan,
Xin Jin,
King H. Yang, and
Albert I. King
Article Category: Research Article
Volume/Issue: Volume 85: Issue 2
Online Publication Date: Feb 01, 2014
Page Range: 130 – 134
Russell T. TurnerPh.D.,
Glenda L. Evans, and
Glenn K. WakleyM.S.
Article Category: Research Article
Volume/Issue: Volume 66: Issue 8
Online Publication Date: Aug 01, 1995
DOI:
Page Range: 770 – 774
Matthew E. MitchellM.D.,
Lawrence S. SternPH.D.,
Nilesh ShahM.D., and
Robert OstrumM.D.
Article Category: Research Article
Volume/Issue: Volume 72: Issue 9
Online Publication Date: Sep 01, 2001
DOI:
Page Range: 790 – 793
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