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likelihood, low consequence, to high likelihood, high consequence. Those of high likelihood or high consequence must be considered for appropriate mission planning. The National Aeronautics and Space Administration (NASA) has produced several lists of spaceflight medical conditions in the past that have been leveraged to create the Informing Mission Planning via Analysis of Complex Tradespaces (IMPACT) 1.0 Medical Condition List. 5 The purpose of this paper is to describe the IMPACT 1.0 Medical Condition List (ICL 1.0), how it was derived, and its application to